Investigating the microbiome of house dust mites in South Korea

Understanding the house dust mites (HDMs) microbiome is crucial due to its potential effects on development of allergic diseases. In 1998, our laboratory collected Dermatophagoides farinae and D. pteronyssinus from beds in a Korean household began cultivating these HDMs. Our has been actively investigating several topics about HDMs recent years, including bacterial fungal their interactions, as well impact HDM airway inflammation. To study microbiome, we employed high-throughput sequencing 16S rDNA amplicons. The results revealed that two most abundant bacteria were Enterococcus faecalis Bartonella spp. contrast, found almost no . By inoculating HDMs, more susceptible than pteronyssinus. This susceptibility was associated with presence certain species Additionally, have recently made efforts produce reduced levels symbiotic bacteria. We believe standardizing controlling are steps for future improvement immunotherapies.